Jordan E Pinsker

MD (Ret)

Lieutenant Colonel, Army

Department of Primary Appointment:
School of Medicine
Pediatrics
Title
Senior Research Physician
Location: Other Location
Research Interests:
Automated Insulin Delivery
Clinical Decision Support Systems for Diabetes

Education

Undergraduate and Medical School 7-Year BS/MD Program:
- Union College, Schenectady, NY, 1994 – 1998
- Albany Medical College, Albany, NY, 1997 – 2001
Internship: Pediatrics, Brooke Army Medical Center, San Antonio, TX, 2001 – 2002
Residency: Pediatrics, Brooke Army Medical Center, San Antonio, TX, 2002 – 2004
Fellowship: Pediatric Endocrinology, National Capital Consortium, Washington, DC, 2004 – 2007

Biography

As the Senior Research Physician, Sansum Diabetes Research Institute, I am the Clinical Trials Director of Artificial Pancreas Studies at our center in Santa Barbara, California. These include NIH, JDRF and industry funded trials, including collaborative studies with numerous partner sites around the world. Our research trials focus on automated exercise detection and treatment in people with diabetes, improving the quality of continuous glucose monitoring devices, testing of algorithms used in the Artificial Pancreas, automated clinical decision support for diabetes, and using all of these technologies to advance the state of closed-loop insulin delivery. I provide clinical input into the design and implementation of Artificial Pancreas devices to improve efficacy and safety, and run all trials related to such devices at our center.

As I am board certified in Clinical Informatics, Pediatric Endocrinology and General Pediatrics, I aim to use my skills in technology and medicine to promote cross-disciplinary scientific advancement in developing advanced technological care for persons with diabetes.

Representative publications, projects, and/or deployments

Ongoing Research Support and Recent Military Awards

:Insulet #G190270. 11/25/2019 – Present. Evaluating the Safety and Effectiveness of the Omnipod Horizon™ Automated Glucose Control System in Patients with Type 1 Diabetes. Role: Co-Investigator

Medtronic #CEP304. 01/24/2019 – Present. Multi-center, Randomized Controlled Trial in Adult and Pediatric Patients with Type 1 Diabetes Using Hybrid Closed Loop System and Control (CSII, MDI and SAP) at Home. Role: Site PI

NIH R01 #DK120358. 09/30/2018 - 05/31/2021. Automated Glucose Regulation to improve Diabetes Control and Outcomes for Pregnant Women with Type 1 Diabetes and Fetus. Role: Co-Investigator

Helmsley Charitable Trust #2018PG-TID061. 04/01/2018 - 03/31/2021. Development of Microneedle-based Sensor to Enhance Automated Insulin Delivery. Role: Co-Investigator

JDRF #2-SRA-2017-503-M-B. 08/01/2017 - 03/31/2021. Harnessing Non-Glucose Feedback Signals for Automatic Glucose Control in Type 1 Diabetes: Confronting Exercise-Safety and Stress-Aware Control. Role: Co-PI

NIH UC4 #DK108483. 01/01/2016 - 12/31/2021. Clinical Acceptance of the Artificial Pancreas: The International Diabetes Closed Loop Trial. Role: Co-Investigator

2019: AMEDD Distinguished Member of the Regiment (DMOR)

2018: Order of Military Medical Merit (O2M3)

2017: The Surgeon General's Physician Recognition Award for Army National Guard Lieutenant Colonel

Bibliography

1. Pinsker JE, Bartee A, Katz ML, Lalonde A, Jones R, Dassau E, Wolpert H. Predictive Low-Glucose Suspend Necessitates Less Carbohydrate Supplementation to Rescue Hypoglycemia: Need to Revisit Current Hypoglycemia Treatment Guidelines. Diabetes Technol Ther. 2021; PMID: 33535013

2. Pinsker JE, Singh H, McElwee Malloy M, Constantin A, Leas S, Kriegel K, Habif S. A Virtual Training Program for the Tandem t:slim X2 Insulin Pump: Implementation and Outcomes. Diabetes Technol Ther. 2021; PMID: 33439754

3. Pinsker JE, Muller L, Constantin A, Leas S, Manning M, McElwee Malloy M, Singh H, Habif S. Real-World Patient Reported Outcomes and Glycemic Improvements with Initiation of Control-IQ Technology. Diabetes Technol Ther. 2021; 23(2):120-127. PMID: 32846114

4. Pinsker JE, Deshpande S, McCrady-Spitzer S, Church M, Kaur R, Perez J, Desjardins D, Piper M, Reid C, Doyle III FJ, Kudva YC, Dassau E. Use of the Interoperable Artificial Pancreas System (iAPS) for Type 1 Diabetes Management During Psychological Stress. J Diabetes Sci Technol. 2021; 15(1):184-185. PMID: 32783473

5. Wolkowicz KL, Aiello EM, Vargas E, Teymourian H, Therani F, Wang J, Pinsker JE, Doyle III FJ, Patti M, Laffel LM, Dassau E. A Review of Biomarkers in the Context of Type 1 Diabetes: Biological Sensing for Enhanced Glucose Control. Bioeng Transl Med. 2021; e10201. DOI: 10.1002/btm2.10201

6. Isganaitis E, Raghinaru D, Ambler-Osborn L, Pinsker JE, Buckingham BA, Wadwa RP, Ekhlaspour L, Kudva YC, Levy CJ, Forlenza GP, Beck RW, Kollman C, Lum JS, Brown SA, Laffel LM, for the iDCL Trial Research Group. Closed-Loop Insulin Therapy Improves Glycemic Control in Adolescents and Young Adults: Outcomes from the International Diabetes Closed-Loop (iDCL) Trial. Diabetes Technol Ther. 2021; PMID: 33216667

7. O’Malley G, Messer L, Levy CJ, Pinsker JE, Forlenza GP, Isganaitis E, Kudva YC, Ekhlaspour L, Raghinaru D, Lum J, Browns SA, for the iDCL Trial Research Group. Clinical Management and Pump Parameter Adjustment of the Control-IQ Closed-loop Control System: Results from a 6-month Multicenter Randomized Clinical Trial. Diabetes Technol Ther. 2021; PMID: 33155824

8. Pinsker JE, Leas S, Muller L, Habif S. Real World Improvements in Hypoglycemia in an Insulin-Dependent Cohort with Diabetes Mellitus Pre/Post Tandem Basal-IQ Technology Remote Software Update. Endocr Pract. 2020; 26(7):714-721. PMID: 33471639

9. Brown SA, Beck RW, Raghinaru D, Buckingham BA, Laffel LM, Wadwa RP, Kudva YC, Levy CJ, Pinsker JE, Dassau E, Doyle III FJ, Ambler-Osborn L, Anderson SM, Church MM, Ekhlaspour L, Forlenza GP, Levister C, Simha V, Breton MD, Kollman C, Lum JW, Kovatchev BP; iDCL Trial Research Group. Glycemic Outcomes of Use of CLC Versus PLGS in Type 1 Diabetes: A Randomized Controlled Trial. Diabetes Care. 2020; 43(8):1822-1828. PMID: 32471910

10. Deshpande S, Pinsker JE, Church M, Piper M, Andre C, Massa J, Doyle III FJ, Eisenberg DM, Dassau E. Randomized Crossover Comparison of Automated Insulin Delivery vs. Conventional Therapy using an Unlocked Smartphone with Scheduled Pasta and Rice Meal Challenges in the Outpatient Setting. Diabetes Technol Ther. 2020; 22(12):865-874. PMID: 32319791