DR. JOSHUA GRAY: Addiction and Psychiatric Genetics (APG) Lab
Dr. Gray’s lab integrates psychiatric genetics, neurobiology, and military health to understand the mechanisms underlying substance use and related psychopathology and to improve outcomes. His work spans two complementary domains: (1) identifying shared genetic architecture and neurobiological pathways linking phenotypes such as alcohol use, other substance use, anxiety, PTSD, and chronic pain; and (2) military health services research focused on improving mental health outcomes for soldiers, particularly those with harmful alcohol use.
Using large-scale genomic approaches (e.g., GWAS, Mendelian randomization, and cross-trait analyses), Dr. Gray's lab seeks to identify mechanisms underlying psychiatric disorders, uncover novel intervention targets, and inform drug repurposing efforts. Dr. Gray leverages Military Health System data to study ways to optimize mental health care delivery and identify modifiable factors influencing outcomes. Additionally, Dr. Gray collaborates on studies investigating emerging treatment approaches, including psychedelic-assisted therapies.
Together, this work seeks to improve the standard of care delivery for service members affected by addiction and related psychiatric disorders.
