WHAT WE DO
All major discoveries that underpin precision medicine come from the fields of Biochemistry and Molecular Biology. In the USU Department of Biochemistry and Molecular Biology, faculty are working on the molecular basis of devastating human diseases including neurodegenerative diseases, autoimmune diseases, infectious diseases, Post-Traumatic Stress Disorder (PTSD), neurodevelopmental disorders, infertility, and cancer. Our faculty are engaged in teaching graduate and medical students who conduct research and provide outstanding medical care in support of the military.
Our research activities, combined with our teaching activities, contribute to public health and DoD by uncovering and communicating knowledge necessary to understand human diseases including those suffered by members of the Uniformed Services.
New publications (since March 2021)
Wang Y, Niu Y, Zhang Z, Gable K, Gupta SD, Somashekarappa N, Han G, Zhao H, Myasnikov AG, Kalathur RC, Dunn TM*, Lee CH*. (2021) Structural insights into the regulation of human serine palmitoyltransferase complexes. Nat Struct Mol Biol. 28::240-248 https://pubmed.ncbi.nlm.nih.gov/33558761/
Saoji M, Sen A, Cox RT (2021) Loss of Mitochondrial Ribonuclease P complex proteins differentially affect mitochondrial tRNA processing in vivo. International Journal of Molecular Sciences, 22(6066). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8200052/
Qiu R, Zhang J, Rotty JD, Xiang X.(2021) Dynein activation in vivo is regulated by the nucleotide states of its AAA3 domain. Curr Biol. Online ahead of print. https://pubmed.ncbi.nlm.nih.gov/34428469/