NON-PHARMACEUTICAL THERAPIES FOR PAIN MANAGEMENT

The development of novel, non-pharmaceutical therapies for pain management is a goal of military medical research. Photobiomodulation therapy (PBMT) is a medical technology that utilizes primarily red or near infrared (NIR) light to induce cellular changes producing beneficial clinical outcomes. This laboratory found that ‘high dose’ PBMT applied transcutaneously reduced pain similarly to peripheral nerve lidocaine injection by a mechanism that specifically disrupted microtubule structure and mitochondria function in nociceptor neurons. PBMT for pain treatment would be non-invasive. PBMT devices can be designed to be light, wearable, and battery operated. Complicated equipment, cold storage, or advanced medical training would not be required. Therefore, the device would be easily deployed and compatible with missions in austere medical environments.

PATENTS RESULTING FROM WORK IN THIS LABORATORY INCLUDE:

Light promotes regeneration and functional recovery after spinal cord injury
Inventors Juanita Anders, Ilko Ilev, Ronald Waynant, Kimberly Byrnes

Light as a Replacement for Mitogenic Factors on Progenitor Cells
Inventors: Anders, J. (USU, APG), Ilev, I. (U.S. Food & Drug Administration), Longo, L. (Institute of Laser Medicine), Waynant, R. (U.S. Food & Drug Administration), and Romanczyk, T. (USU, APG).

 

3

ongoing research projects

51

partners in the last five years

25

student publication in the last 30 years

75

faculty publications in 26 different journals in the last 30 years