Prasanna Satpute-Krishnan


Department of Primary Appointment:
School of Medicine
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Cell Biology
Protein Trafficking and Quality Control
Office Phone


Postdoctoral Training: Jennifer Lippincott-Schwartz Lab at National Institutes of Health, Bethesda, MD

Graduate Education: Ph.D. in Molecular Biology, Cell Biology and Biochemistry at Brown University, Providence, RI
Thesis title: "Mechanistic Insights Into Prion Propagation by Monitoring Protein Dynamics In Vivo"

Representative publications, projects, and/or deployments

2014 Bernfield Award for Excellence in Research, American Society for Cell Biology

2007 Joukowsky Award for the top thesis in the life sciences, Brown University


Sengupta P, Satpute-Krishnan P, Seo A, Burnette DT, Patterson G, and Lippincott-Schwartz J, ER trapping reveals Golgi enzymes continually revisit the ER through a recycling pathway that controls Golgi organization. Proc Natl Acad Sci USA 2015 Dec 8; 112(49): E6752-61

Satpute-Krishnan P, Ajinkya M, Bhat S, Hegde RS, Lippincott-Schwartz J. ER stressinduced clearance of misfolded GPI-anchored proteins via the secretory pathway. Cell. 2014 July 31; 158(3):522-33**

Hailey DW, Rambold AS, Satpute-Krishnan P, Mitra K, Sougrat R, Kim PK, Lippincott- Schwartz J. Mitochondria supply membranes for autophagosome biogenesis during starvation Cell. 2010 May 14; 141(4):656-67.

Satpute-Krishnan P, Langseth SX, Serio TR. Hsp104-dependent remodeling of prion complexes mediates protein-only inheritance. PLoS Biol. 2007 Jan; 5(2):e24.

Satpute-Krishnan P, Serio TR. Prion protein remodelling confers an immediate phenotypic switch. Nature. 2005 Sep 8; 437(7056):262-5.