Pushpa Sharma


Department of Primary Appointment:
School of Medicine
Associate Professor
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
TBI, PTSD, Hemorrhagic Shock, Mitochondria
Biomarkers and treatments
Office Phone


1982. All India Institute of Medical Sciences, New Delhi, India. Ph.D. Public Health Sciences (Gastroenterology)


Dr. Sharma received several international post-doctorate fellowships such as: 1. Commonwealth Foundation Research Fellowship in Gastroenterology at Royal Postgraduate Medical School and Hammersmith hospital London, England, 2. Post-doctorate fellowship in Gastroenterology at Karolinska Medical Institute, Stockholm, Sweden and 3. NSERC fellowship in Neurosciences at the University of Western Ontario, London, Ontario Canada. Dr. Sharma also worked as a Research Associate at the University of Western Ontario, London, Ontario Canada to study the mitochondrial functions and mutations in inherited metabolic disorders. Dr. Sharma subsequently moved to United States to join Dr. Ajay Varma's lab at Uniformed Services University of the Health Sciences, Bethesda,MD as Research Associate to work on mitochondrial functions, oxygen and fuel sensing, and cell signalling in TBI and cancer. Dr. Sharma is now Research Associate Professor and Research Director in Anesthesiology Department. She is also running a well funded lab on mitochondrial targeted diagnostic and therapeutic strategies in TBI, PTSD, hemorrhagic shock, and polytrauma in animal models.

Representative publications, projects, and/or deployments

Recent awards includes 1. Deans Impact Award and 2. Dean's fellowship


Sumit Sinha, Amol Raheja, Neha Samson, Sanjeev Bhoib, Arul Selvi, Pushpa Sharma. Blood mitochondrial enzymatic assay as predictor of long-term outcome in severe traumatic brain injury. J. Clinical Neuroscience, 2016.30:31-8

Raheja A, Sinha S, Samson N, Bhoi S, Subramanian A, Sharma P, Sharma BS. Serum biomarkers as predictors of long-term outcome in severe traumatic brain injury: analysis from a randomized placebo-controlled Phase II clinical trial. J Neurosurg. 2016. 1:1-11.

Guoqiang Xing1, Erin S. Barry2, Brandi Benford1, Neil E. Grunberg2, He Li3, William D. Watson4 and Pushpa Sharma1* (Senior and corresponding author). Impact of Repeated Stress on Traumatic Brain Injury-Induced Mitochondrial Electron Transport Chain Expression and Behavioral Responses in Rats. Front Neurol. 2013; 4: 196-10.

Sharma P and Mongan P.D. Sodium pyruvate is better than ethyl pyruvate in preventing liver damage after hemorrhagic shock. J. Shock. 2010; 33: 532-8.

Sharma P, Benford B and Ling GS. Pyruvate prevents traumatic brain injury through the activation of pyruvate dehydrogenase complex- measurement of pyruvate dehydrogenase complex by dipstick test. Journal of Emergencies, Trauma and Shock, 2009; 21: 67-5.