Volodymyr Pidoplichko

Ph.D.

Department of Primary Appointment:
School of Medicine
Anatomy, Physiology and Genetics
Title
Research Associate Professor
Location: Walter Reed National Military Medical Center, Bethesda, MD
Research Interests:
The role of CNS ligand-gated ion channels in Amygdala
Modulation of Amygdala network by Acid Sensitive Ion Channels (ASIC1aRs)
Email
volodymyr.pidoplichko.ctr@usuhs.edu

Education

Faculty of Physics of Shevchenko State University in Kyiv, Ukraine. Ph.D. in biophysics and electrophysiology from Bogomoletz Institute of Physiology, Kyiv, Ukraine.

Biography

NAME: Volodymyr Pidoplichko

ACADEMIC TRAINING:
1965 - 1970 Kiev State University (Faculty of Physics, B.S. in Molecular Physics)

1969 -1972,
1974 -1975 Ph.D. ( “Candidate of Biol. Sciences” ) Bogomoletz Institute of Physiology, Ukr.
Acad. Sci., Kyiv, Ukraine
1975 - 1987 “Doctor of Biol. Sciences“ , senior sci. degree

EMPLOYMENT:
1970 - 1972 Research Fellow with Dr. P.G.Kostyuk,
Bogomoletz Institute of Physiology, Kiev, Ukraine
1972 - 1974 Lieutenant-Engineer, radar specialist, Soviet Air Force
1974 - 1980 Junior Research Scientist,
Dr. P.G.Kostyuk, Chairman,
Bogomoletz Institute of Physiology, Kiev, Ukraine
1980 - 1988 Senior Research Scientist, Bogomoletz Institute of Physiology, Kiev, Ukraine
1988 - 1989 Senior Research Scientist,
Dr. Yu. Yu. Gleba, Dept. Head,
Div. of Cell Biology and Engineering, Institute of Botany, Kiev, Uktaine
1989 - 1990 Head of the Laboratory of Molecular Physiology,
Dr. Yu. Yu. Gleba, Chairman,
Institute of Cell Biology and Engineering, Kiev, Ukraine
1991 - 1992 Head of the Department of Membranology and Phytochemistry,
Dr. K.M.Sytnik, Chairman,
Institute of Botany, Kiev, Ukraine
1992 - 1995 Research Scientist,
Dr. K. G. Reymann, Dept. Head,
Institute for Neurobiology, Magdeburg, Germany
1995 - 1996 Head of the Dep. of Membranology and Phytochemistry,
Dr. K.M.Sytnik, Chairman,
Institute of Botany, Kiev, Ukraine
1996 - 2006 Research Associate/Instructor,
Dr. John A. Dani,
Div. of Neuroscience, Baylor College of Medicine, Houston, USA
2007-2014 Research Associate
Prof. Dr. Maria F. Braga,
Dep. of Anatomy, Physiology and Genetics, Uniformed Services
University of the Health Sciences, Bethesda, USA
2014-present Research Associate Professor
Prof. Dr. Maria F. Braga,
Dep. of Anatomy, Physiology and Genetics, Uniformed Services
University of the Health Sciences, Bethesda, USA

Career Highlights: Positions, Projects, Deployements, Awards and Additional Publications

1983 Recipient State prize USSR Council of Ministers

Pidoplichko V.I. & Verkhratsky A.N. (1984) Possible existence of tetrodotoxin-sensitive voltage-dependent chloride conductance in the membrane of perfused cardiomyocytes. Doklady Akad. Nauk SSSR, Moscow, v.279, pp.1012-1015 (in Russian)

Wilsch V.W., Pidoplichko V.I., Opitz T., Shinozaki H. & Reymann K.G. (1994) Metabotropic glutamate receptor agonist DCG-IV as NMDA receptor agonist in immature rat hippocampal neurons. Eur. J. Pharmacol. v.262, pp.287-291

Pidoplichko V.I., Wilsch V.W. & Reymann K.G. (1996) Fast desensitizing kainate-gated current resolved in whole-cell experiments on isolated rat hippocampal neurons. Eur. J. Pharmacol., v. 303, pp.145-149

Pidoplichko V.I. (1996) Dependence of solution exchange time on cell or patch linear dimensions in concentration jump experiments using patch-clamped sensory neurons. Pflugers Arch. - Eur. J. Physiol. v. 432, pp. 1074-1079

Pidoplichko VI, Dani JA. (2005) Applying small quantities of multiple compounds to defined locations of in vitro brain slices. J Neurosci Methods. v.142(1), pp.55-66.

Pidoplichko VI, Dani JA. (2006) Acid-sensitive ionic channels in midbrain dopamine neurons are sensitive to ammonium, which may contribute to hyperammonemia damage. Proc Natl Acad Sci U S A. v.103(30) pp.11376-80.

Representative Bibliography

Kostyuk P.G., Krishtal O.A. & Pidoplichko V.I. (1972) Potential-dependent membrane current during the active transport of ions in snail neurones. J.Physiol., London, v.226, pp.373-392

Krishtal O.A. & Pidoplichko V.I. (1975) Intracellular perfusion of snail giant neurons. Neirofiziologiya, Kiev, v.7, pp.327-329 (in Russian)

Kostyuk P.G., Krishtal O.A. & Pidoplichko V.I. (1975) Effect of internal fluoride and phosphate on membrane currents during intracellular dialysis of nerve cells. Nature, London, v.257, pp.691-693

Kostyuk P.G., Krishtal O.A. & Pidoplichko V.I. (1977) Asymmetrical displacement currents in nerve cell membrane and effect of internal fluoride. Nature, London, v.267, pp.70-72

Krishtal O.A. & Pidoplichko V.I. (1980) A receptor for protons in the nerve cell membrane. Neuroscience, v.5, pp.2325-2327

Kostyuk P.G., Krishtal O.A. & Pidoplichko V.I. (1981) Calcium inward current and related charge movements in the membrane of snail neurones. J.Physiol., London, v.310, pp.403-421

Krishtal O.A., Marchenko S.M. & Pidoplichko V.I. (1983) Receptor for ATP in the membrane of mammalian sensory neurones. Neuroscience Letters, v.35, pp.41-45

Pidoplichko V.I. (1992) Ammonia and proton-gated channel populations in trigeminal ganglion neurons. Gen Physiol. Biophys., v.11, pp.39-48

Pidoplichko V.I. , DeBiasi M., Williams J.T. & Dani J.A.(1997) Nicotine activates and desensitizes midbrain dopamine neurons. Nature, v.290, pp. 401-404

Pidoplichko V.I., Aroniadou-Anderjaska V, Prager E.M., Figueiredo T.H., Almeida-Suhett C.P., Miller S.L. & Braga M.F. (2014) ASIC1a activation enhances inhibition in the Basolateral Amygdala and reduces anxiety. J.Neuroscience, v.34(9), pp.3130-3141