Elke S Bergmann-Leitner
EducationPostdoctoral fellow 1992-1996: National Cancer Institute/ NIH Bethesda, MD
Ph.D. 1992 -summa cum laude- (Distribution of T-cells, B-cells and ED-1 positive macrophages in spleen and autotransplanted splenic tissue after intravenous immunization: a comparison of the effect of soluble and cellular antigen from Escherichia coli). Institute of Chemistry and Biochemistry at the University of Salzburg
M.S. 1990: (Regeneration of autotransplanted splenic tissue in the course of time),Institute for Biology, Biochemistry and Biophysics, Department of Biochemistry
University of Salzburg/Austria
Representative publications, projects, and/or deployments
Nov 2017: Research Prof. Dept Medicine USUHS
October 2014- present: Science and Technology Manager Level III (Army AT&L Workforce)
August 2013- present: Chief Flow Cytometry Center, US Military Malaria Research Program
February 2001- Jan 2014: Research Scientist, WRAIR (Characterization of anti-malaria immune responses induced by DNA vaccines; functional characterization of growth- and invasion-inhibitory antibodies against blood stages of P.falciparum; development of high-throughput functional assays for vaccine evaluation, characterization of novel malarial antigens as vaccine candidates); Contractor Clinical Research Management
July 1998-January 2001: Research Fellow, LTIB/NCI/NIH (Development of model systems for the study of tumor escape mechanisms)
Apr.1996-July 1998: Visiting Associate, LTIB/NCI/NIH (Human T-cell responses to point mutated ras oncogenes in healthy individuals and cancer patients)
Editorial board member:Clinical Immunology Infection and Immunity
complete publication list: http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/bibliography/48798681/descending
Presentation of novel flow cytometric methods - https://www.youtube.com/watch?v=o1zQXGHfAZI
TREY A. KNEPPER, ELIZABETH H. DUNCAN, TATYANA SAVRANSKY ELKE S. BERGMANN-LEITNER. Novel ELISA method as exploratory tool to assess immunity induced by radiated attenuated sporozoites to decipher protective immunity. Mal J 2017 (16); e 484
CHAUDHURY S, DARKO C, REGULES JA, DUTTA S, WALLQVIST A, JONGERT E, WATERS NC, LEMIALE F, BERGMANN-LEITNER E. Delayed fractional dose regimen of the RTS,S/AS01 malaria vaccine candidate enhances an IgG4 response that inhibits serum opsono-phagocytosis"
FAROOQ F., BECK, K., PAOLINO K.M., PHILLIPS R. WATERS NC, REGULES, JA, BERGMANN-LEITNER E.S. Circulating follicular T helper cells and cytokine profile in humans following vaccination with the rVSV-ZEBOV Ebola vaccine
CHAUDHURY S, OCKENHOUSE CF, REGULES JA, DUTTA S, WALLQVIST A, JONGERT E, WATERS NC, LEMIALE F, BERGMANN-LEITNER E. The biological function of antibodies induced by the RTS,S/AS01 malaria vaccine candidate is determined by their fine specificity.
FAROOQ F, BERGMANN-LEITNER ES. Immune Escape Mechanisms are Plasmodium's Secret Weapons Foiling the Success of Potent and Persistently Efficacious Malaria Vaccines.
BERGMANN-LEITNER, ES, CHAUDHURY S. Simulating the immune response.
BERGMANN-LEITNER ES, LI Q, CARIDHA D, O’NEIL MT, OCKENHOUSE CF, HICKMAN M, ANGOV E. Protective immune mechanisms against pre-erythrocytic forms of Plasmodium berghei depend on the target antigen.
BERGMANN-LEITNER ES, CHAUDHURY S, STEERS NJ, SABATO M, DELVECCHIO V, WALLQVIST AS, OCKENHOUSE CF, ANGOV E. Computational and experimental validation of B and T-cell epitopes of the in vivo immune response to a novel malarial antigen.
BERGMANN-LEITNER E., HOSIE H, TRICHILO J, DERISO E, RANALLO R, ALEFANTIS, SAVRANSKAYA T, GREWAL P, OCKENHOUSE O, VENKATESAN M, DELVECCHIO V, ANGOV E. Self-adjuvanting bacterial vectors expressing pre-erythrocytic antigens induce sterile protection against malaria.
BERGMANN-LEITNER E. S., DUNCAN E.H., MEASE R.M., ANGOV E Impact of pre-existing MSP1-42 allele-specific immunity on potency of an erythrocytid Plasmodium falciparum vaccine.