Saibal Dey PhD

Education

Ph.D., Biochemistry, Wayne State University School of Medicine, Detroit, Michigan (1994)
M. Sc., Zoology, Specialization: Cell Biology, University of Burdwan, West Bengal, India (1985)
B. Sc., Zoology, Minor: Botany and Chemistry, University of Burdwan, West Bengal, India (1983)

Career Highlights: Positions, Projects, Deployements, Awards and Additional Publications

Vice Chair, Department of Biochemistry

Dean's Fellow, Uniformed Services University School of Medicine, (2018)

Module Director, Foundation in Medicine Module, Molecules to Military Medicine Curriculum, USU School of Medicine

"School of Medicine Dean's Teaching Award" in Basic Science, Uniformed Services University School of Medicine (2017)

“Hébert Impact Award” for outstanding contribution to the mission of the School, Uniformed Services University School of Medicine (2016)

“Hébert Impact Award” for outstanding contribution to the mission of the School, Uniformed Services University School of Medicine (2015)

“Recognition For Exemplary Support of the Molecules to Military Medicine Curriculum” Uniformed Services University School of Medicine Curriculum Reform (2011)

“Plank Holders of the Molecules to Military Medicine Curriculum”, for contribution to curriculum reform, Dean’s Office, Uniformed Services University School of Medicine (2011)

“Fellows Award for Research Excellence”, National Institutes of Health, Bethesda, Maryland. (1999)

“AACR-Genetics Institute Young Investigator Award”, in the annual meeting of The American Association For Cancer Research (1998)

Representative Bibliography

Mandal, D., Moitra, K., Ghosh, D., Xia, D. and Dey, S. (2012) Evidence for modulatory sites at the lipid-protein interface of the human multidrug transporter P-glycoprotein. Biochemistry 51:2852-2866

Data, S., Mazumder, S., Ghosh, D., S., Dey, S., and Bhattacharya, S. (2009) Low concentration of arsenic induce caspase-3 mediated head kidney macrophage apoptosis with JNK-p38 activation in Claris batrachas. Toxicology and Applied Pharmacology 241:329-338

Fong, W. F., Wan, C. K., Zhu, G. Y., Chattopadhyay, A., Dey S., Zhao, Z., and Shen, X. L. (2007) Schisandrol A from Schisandra chnensis reverses P-glycoprotein-mediated multidrug resistance by affecting Pgp-substrate complexes. Planta Medica, 73: 212-220.

Wan, C. K., Zhu, G. Y., Shen, X. L., Chattopadhyay, A., Dey, S., and Fong, W. F. (2006) Gomisin A alters substrate interaction and reverses P-glycoprotein mediated multidrug resistance in HepG2-DR cells. Biochemical Pharmacology, 72(7): 824-37

Maki, N., and Dey, S. (2006) Biochemical and pharmacological properties of an allosteric modulator site of human P-glycoprotein. Biochemical Pharmacology 72(2): 145-155

Maki, N., Moitra, K., Ghosh, P., and Dey, S. (2006) Allosteric modulation bypasses requirement for ATP hydrolysis in regenerating low-affinity transition state conformation of human P-glycoprotein. Journal of Biological Chemistry. 281(16): 10699-10777

Ghosh, P., Moitra, K., Maki, N., and Dey, S. (2006) Allosteric modulation of the human P-glycoprotein involves conformational changes mimicking catalytic transition intermediates. Archives of Biochemistry and Biophysics. 450 (1): 100-112

Maki, N., Moitra, K., Silver, C., Ghosh, P., Chattopadhyay, A. K., and Dey, S. (2006) Modulator induced interference in functional cross talk between the substrate- and the ATP- sites of human P-glycoprotein. Biochemistry 45: 2739-2751

Maki, N., Hafkemeyer, P., and Dey, S. (2003). Allosteric modulation of human P-glycoprotein: Inhibition of transport by preventing substrate translocation and dissociation. Journal of Biological Chemistry. 278(20): 18132-18139.

Dey, S. (2002) Biricodar (Vertex Pharmaceuticals). Current Opinion in Investigational Drugs, Vol. 3(5): 818-823.