Teri A Manolio


Department of Primary Appointment:
School of Medicine
Professor of Medicine
Location: Walter Reed National Military Medical Center, Bethesda, MD
Research Interests:
Incorporating genomic findings into clinical care
Genome-wide association studies of complex diseases, ethnic differences in disease risk
Office Phone


1973-1976 University of Maryland at College Park, Bachelor of Science in Biochemistry
1976-1980 University of Maryland at Baltimore, Doctor of Medicine
1985-1987 The Johns Hopkins University School of Hygiene and Public Health, Master of Health Sciences in Epidemiology
1998-2001 The Johns Hopkins University School of Hygiene and Public Health, Doctor of Philosophy, Human Genetics/Genetic Epidemiology

Representative publications, projects, and/or deployments

1980-1983- Boston City Hospital, Straight Medical Intern and Resident

1983-1984- District of Columbia General Hospital, Chief Medical Resident, Georgetown Service

1984-1987- The Johns Hopkins Medical Institutions, Fellow, Division of Internal Medicine

1987-1994- Medical Officer, Clinical and Genetic Epidemiology Branch, National Heart, Lung, and Blood Institute

1994-2005- Director, Epidemiology and Biometry Program, National Heart, Lung, and Blood Institute

2005-2007- Senior Advisor to the Director, NHGRI, for Population Genomics, National Human Genome Research Institute

2007-2012- Director, Office of Population Genomics, National Human Genome Research Institute

2012- Director, Division of Genomic Medicine, National Human Genome Research Institute

1990- Fellow, American Heart Association, Council on Epidemiology

2003- Fellow, American College of Physicians


Manolio TA, Collins FS. Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, Cho JH, Guttmacher AE, Kong A, Kruglyak L, Mardis E, Rotimi CN, Slatkin M, Valle D, Whittemore AS, Boehnke M, Clark A, Eichler EE, Gibson G, Haines JL, Mackay TFC, McCarroll SA, Visscher PM. Finding the missing heritability of complex diseases. Nature 2009; 461:747-53.

Manolio TA. Genome-wide association studies and disease risk assessment. New England Journal of Medicine 2010; 363:166-76.

Manolio TA, Chisholm RL, Ozenberger B, Roden DM, Williams MS, Wilson R, Bick D, Bottinger EP, Brilliant MH, Eng C, Frazer KA, Korf B, Ledbetter DH, Lupski JR, Marsh C, Mrazek D, Murray MF, O’Donnell PH, Rader D, Relling MV, Shuldiner AR, Valle D, Weinshilboum R, Green ED, Ginsburg GS. Implementing genomic medicine in the clinic: The future is here. Genetics in Medicine 2013; 15:258-67.

Manolio TA. Bringing genome-wide association findings into clinical use. Nature Reviews Genetics 2013; 14:549-58.

Manolio TA, Murray MF, for the Inter-Society Coordinating Committee on Practitioner Education in Genomics.. The growing role of professional societies in educating clinicians in genomics. Genetics in Medicine 2014; 16:571-72.

MacArthur DG, Manolio TA, Dimmock DP, Rehm HL, Shendure J, Abecasis GR, Adams DR, Altman RB, Antonarakis SE, Ashley EA, Barrett JC, Biesecker LG, Conrad DF, Cooper GM, Cox NJ, Daly MJ, Gerstein MB, Goldstein DB, Hirschhorn JN, Leal SM, Pennacchio LA, Stamatoyannopoulos JA, Sunyaev SR, Valle D, Voight BF, Winckler W, Gunter C. Guidelines for investigating causality of sequence variants in human disease. Nature. 2014; 508:469-76.

Manolio TA, Abramowicz M, Al-Mulla F, Anderson W, Balling R, Berger AC, and et al. Global Implementation of Genomic Medicine: We are not Alone. Sci Tranl Med. 2015 Jun 3;7(290):290ps13. doi: 10.1126

Manolio TA, Fowler DM, Starita LM, Haendel MA, MacArthur DG, Biesecker LG, Worthey E, Chisholm RL, Green ED, Jacob HJ, McLeod HL, Roden D, Rodriguez LL, Williams MS, Cooper GM, Cox NJ, Herman GE, Kingsmore S, Lo C, Lutz C, MacRae CA, Nussbaum RL, Ordovas JM, Ramos EM, Robinson PN, Rubinstein WS, Seidman C, Stranger BE, Wang H, Westerfield M, Bult C. Bedside back to bench: Building bridges between basic and clinical genomic research. Cell 2017; 169:6-12.

Manolio TA. Incorporating whole-genome sequencing into primary care: Falling barriers and next steps. Annals of Internal Medicine 2017; 167:204-205.

Manolio TA, Hutter C, Avigan M, Cibotti R, Davis RL, Denny JC, La Grenade L, and et al. Research directions in genetically mediated Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis. Clinical Pharmacology and Therapeutics 2017; Nov 6. doi: 10.1002/cpt.890 [Epub ahead of print].