Stephen Davies B.V.Sc., Ph.D.

Education

B.V.Sc. ~ School of Veterinary Science, University of Bristol, United Kingdom, 1993
Ph.D. ~ College of Veterinary Medicine, Cornell University, United States, 1998
Postdoctoral Fellow ~ Department of Pathology, University of California San Francisco, United States, 1998-2004

Biography

Current Research Interests:
• Elucidation of host factors that modulate schistosome blood fluke development
• Initiation of innate immune responses by schistosomes and other helminths
• Immune evasion by schistosomes and other helminths
• Role of helminth proteases in immune responses to helminths
• Elucidation of helminth signaling pathways that transduce host signals
• Exploitation of helminth protein kinases as novel drug targets
• Mucosal immune responses to Enteroaggregative Escherichia coli

Representative Bibliography

Riner, D.K., Ferragine, C.E., Maynard, S.K., Davies, S.J. (2013) Regulation of innate responses during pre-patent schistosome infection provides an immune environment permissive for parasite development. PLoS Pathogens 2013;9(10):e1003708. doi: 10.1371/journal.ppat.1003708

Lamb, E.W., Walls, C.D., Pesce, J.T., Riner, D.K., Maynard, S.K., Crow, E.T., Wynn, T.A., Schaefer, B.C., and Davies, S.J. (2010) Blood fluke exploitation of non-cognate CD4+ T cell help to facilitate parasite development. PLoS Pathogens 6(4):e1000892

Swierczewski, B.E. and Davies, S.J. (2009) A Schistosome cAMP-Dependent Protein Kinase Catalytic Subunit is Essential for Parasite Viability. PLoS Negl. Trop. Dis. 3(8), e505

Davies, S.J., Grogan, J.L., Blank R.B., Lim, K.C., Locksley, R.M. and McKerrow, J.H. (2001) Modulation of Blood Fluke Development in the Liver by Hepatic CD4+ Lymphocytes. Science 294, 1358-1361