David M. Burmeister
Education08/06-08/11 Wake Forest University Health Sciences, Winston-Salem, NC- Ph.D.- Physiology and Pharmacology
08/01-05/05 College of Charleston Honors Program, Charleston, SC- BS- Biology / Pre-Pharmacy, 2005
BiographyAs an independent research physiologist, my early professional career has involved studies that examine the body’s natural response to trauma, in an attempt to understand and recapitulate successful healing responses. My primary scientific interests are translational in nature, and include the role of fluid resuscitation in organ (dys)function and inflammation, burn wound healing and diagnosis, and the role of the microbiome on physiological homeostasis. My doctoral studies were performed at the Wake Forest Institute of Regenerative Medicine and examined successful, age-dependent, regeneration of the urinary bladder after surgical trauma. My interest in military medicine began at the US Army Institute for Surgical Research where I completed a three-year postdoctoral fellowship examining burn trauma and wound healing strategies. There, I became interested in critical care, and the use of resuscitative fluids to treat different types of trauma, which was supported by an award through the Congressionally Directed Medical Research Program. With infectious complications at the crux of outcomes in burn and other forms of trauma, I have interest in the exciting world of the microbiome on skin and within the gut. In short, my career thus far has revolved around translational research by studying natural (patho)physiologic consequences, and therapies to recapitulate beneficial responses, and circumvent aberrant ones.
McIntyre MK, Winkler CJ, Gómez BI, Lapierre JP, Little JS, Dubick MA, Nicholson SE, Burmeister DM. The Effect of Burn Resuscitation Volumes on the Gut Microbiome in a Swine Model. Shock. 2020 Sep;54(3):368-376.
Chao T, Gomez BI, Heard TC, Dubick MA, Burmeister DM. Increased oxidative phosphorylation in lymphocytes does not atone for 1 decreased cell numbers after burn injury. Innate Immun. Innate Immun. 2020 Jul;26(5):403-412.
Burmeister DM, Johnson TR, Lai Z, Scroggins S, DeRosa M, Jonas RB, Zhu C, Scherer E, Stewart RM, Schwacha MG, Jenkins DH, Eastridge BJ, Nicholson SE. The Gut Microbiome Distinguishes Mortality in Trauma Patients Upon Admission to the Emergency Department. J Trauma Acute Care Surg. 2020 May;88(5):579-587
Gómez BI, Dubick MA, Schmidt EP, Shupp JW, Burmeister DM. Plasma and Urinary Glycosaminoglycans as Evidence for Endotheliopathy in a Swine Burn Model. J Surg Res. 2020 Apr;248:28-37.
Chao T, Gómez BI, Heard TC, Smith BW, Dubick MA, Burmeister DM. Burn-Induced Reductions in Mitochondrial Abundance and Efficiency are More Pronounced with Small Volumes of Colloids in Swine. Am J Physiol Cell Physiol. Am J Physiol Cell Physiol. 2019 Dec 1;317(6):C1229-C1238.
Johnson TR, Gomez BI, McIntyre MK, Dubick MA, Christy RJ, Nicholson SE, Burmeister DM. The Cutaneous Microbiome and Wounds: New Molecular Targets to Promote Wound Healing. Int J Mol Sci. 2018 Sep 11;19(9). pii: E2699. doi: 10.3390/ijms19092699.
Gomez BI, He C, Chao T, Dubick MA, Burmeister DM. Effect of Intravenous Fluid Volumes on the Adrenal Glucocorticoid Response after Burn Injury in Swine. J Burn Care Res. 2018 Aug 17; 39(5):652-660.
Gomez BI, McIntyre MK, Gurney JM, Chung KK, Cancio LC, Dubick MA, Burmeister DM. Enteral Resuscitation with Oral Rehydration Solution to Reduce Acute Kidney Injury in Burn Victims: Evidence from a Porcine Model. PLoS One. 2018 May 2;13(5):e0195615.
Burmeister DM, Stone II R, Wrice N, Laborde A, Becerra S, Natesan S, Christy R. Delivery of Allogeneic Adipose Stem Cells in PEG-Fibrin Hydrogels as an Adjunct to Meshed Autografts After Debridement of Deep Partial Thickness Burns. Stem Cell Trans Med. 2018 Apr; 7(4): 360-372.
McIntyre M, Peacock T, Akers K, Burmeister DM. Initial Characterization of the Pig Skin Bacteriome and its Effect on in vitro Models of Wound Healing. PLoS One. 2016 Nov 8; 11(11): e0166176.