Gregory P Holmes-Hampton


Department of Primary Appointment:
School of Medicine
Pharmacology & Molecular Therapeutics
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Office Phone


Post Doctoral Fellowship, NICHD/NIH Bethesda, MD
Ph.D. in Chemistry, Texas A&M University, College Station, TX
B.S. in Chemistry, Illinois State University, Normal, IL


Bene BJ, Blakely WF, Burmeister DM, Cary L, Chhetri SJ, Davis CM, Ghosh SP, Holmes-Hampton GP, Iordanskiy S, Kalinich JF, Kiang JG, Kumar VP, Lowy RJ, Miller A, Naeem M, Schauer DA, Senchak L, Singh VK, Stewart AJ, Velazquez EM, Xiao M. Celebrating 60 Years of Accomplishments of the Armed Forces Radiobiology Research Institute1. Radiat Res. 2021 May 12. doi: 10.1667/21-00064.1. Epub ahead of print. PMID: 33979439.

Y Aghdam S, Kenchegowda D, Holmes-Hampton GP, Moroni M, P Ghosh S. Impairment of IGF-1 Signaling and Antioxidant Response Are Associated with Radiation Sensitivity and Mortality. Int J Mol Sci. 2021 Jan 5;22(1):451. doi: 10.3390/ijms22010451. PMID: 33466349; PMCID: PMC7795011.

Aghdam SY, Kenchegowda D, Sharma NK, Holmes-Hampton GP, Legesse B, Moroni M, Ghosh SP. Dysregulated Cardiac IGF-1 Signaling and Antioxidant Response Are Associated with Radiation Sensitivity. Int J Mol Sci. 2020 Jul 17;21(14):5049. doi: 10.3390/ijms21145049. PMID: 32708958; PMCID: PMC7404117.

Hritzo B, Aghdam SY, Legesse B, Kaur A, Cao M, Boerma M, Chakraborty N, Dimitrov G, Gautam A, Hammamieh R, Wilkins W, Tsioplaya A, Holmes-Hampton GP, Moroni M. Late Health Effects of Partial Body Irradiation Injury in a Minipig Model Are Associated with Changes in Systemic and Cardiac IGF-1 Signaling. Int J Mol Sci. 2021 Mar 23;22(6):3286. doi: 10.3390/ijms22063286. PMID: 33807089; PMCID: PMC8005067.

Sharma NK, Holmes-Hampton GP*, Kumar VP, Biswas S, Wuddie K, Stone S, et al. Delayed effects of acute whole body lethal radiation exposure in mice pre-treated with BBT-059. Scientific Reports. 2020;10(1):6825.

Satyamitra M, Cary L, Dunn D, Holmes-Hampton GP, Thomas LJ, Ghosh SP. CDX-301: a novel medical countermeasure for hematopoietic acute radiation syndrome in mice. Sci Rep. 2020;10(1):1757.

Chakraborty N, Gautam A, Holmes-Hampton GP, Kumar VP, Biswas S, Kumar R, et al. microRNA and Metabolite Signatures Linked to Early Consequences of Lethal Radiation. Sci Rep. 2020;10(1):5424.

Sharma NK, Stone S, Kumar VP, Biswas S, Aghdam SY, Holmes-Hampton GP, et al. Mitochondrial Degeneration and Autophagy Associated With Delayed Effects of Radiation in the Mouse Brain. Front Aging Neurosci. 2019;11:357.

Maio N, Kim KS, Holmes-Hampton G, Singh A, Rouault TA. Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis. Haematologica. 2019;104(9):1756-67.

Holmes-Hampton GP, Ghosh MC, Rouault TA. Methods for Studying Iron Regulatory Protein 1: An Important Protein in Human Iron Metabolism. Methods Enzymol. 2018;599:139-55.