Education1999 B.S. Biology (with Honors), University of South Dakota, Vermillion, SD
2004 Ph.D. Immunology, University of Iowa, Iowa City, IA
BiographyDr. Lees started his career by training in T cell biology and cellular cancer immunotherapy. During his subsequent postdoctoral fellowship at he focused on the interactions between T cells and host tissue during autoimmune reactions, particularly focusing on autoimmune neuroinflammation. He then moved on to further investigations of autoimmune inflammation with studies on type I diabetes and a continued focus on neuroinflammation which remains active within the lab.
Representative publications, projects, and/or deployments
W.M. Keck Postdoctoral Program in Molecular Medicine at Washington University Fellowship: W.M. Keck Postdoctoral Program in Molecular Medicine Washington University School of Medicine
National Multiple Sclerosis Society Fellowship
Clark AA, Nurmukhambetova S, Li X, Munger SD, Lees JR#. Odorants specifically modulate chemotaxis and tissue retention of CD4+ T cells via cyclic adenosine monophosphate induction. Journal of Leukocyte Biology, 2016 Oct;100(4):699-70
Li X, Lees JR. Pre-existing central nervous system lesions negate cytokine requirements for regional experimental autoimmune encephalomyelitis development. Immunology, 2013 Mar;138(3):208-15.
Lees JR, Golumbek PT, Sim J, Russell JH. Regional CNS responses to IFN-gamma determine lesion localization patterns during EAE pathogenesis. Journal of Experimental Medicine 2008 Oct 27; 205(11):2633-42