David S. Krantz


Department of Primary Appointment:
School of Medicine
Medical and Clinical Psychology
Professor of Medical and Clinical Psychology; Professor of Psychiatry (secondary)
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Behavioral medicine and cardiovascular disease
Psychosocial stress and human health
Office Phone


Education: B.S. (1971) in Psychology, City College of New York.
Ph.D. (1975) in Psychology, University of Texas at Austin.


Dr. Krantz's broad research interests are on the effects of psychosocial stress on health, and the role of psychological factors in cardiovascular disease. For more than 30 years, his primary focus has been on the effects of acute stress as a trigger of coronary heart disease events, and he has published more than 180 scientific and professional papers in these areas. In his current research, he is Principal Investigator of the BETRHEART Study, which investigates stress and psychosocial factors in the progression of heart failure. In other projects, he collaborates with investigators in the USUHS Psychiatry Department's Center for the Study of Traumatic Stress on studies of the effects of stress and bereavement on physical health in military populations, and PTSD and sleep disorders in relation to cardiovascular disease. He particularly interested in understanding relationships of PTSD to cardiovascular disease and other physical health problems, with an emphasis on PTSD as a "whole body" systemic disorder, rather than as a purely mental health problem.

Dr. Krantz was formerly Chair of the USUHS Department of Medical and Clinical Psychology between 1999-2014, and was one of a group of founders of the USU Center for Deployment Psychology (CDP), and CDP Principal Investigator between 2006-2015. In the past, he has served as Editor-in-Chief of the APA journal Health Psychology, president of the Health Psychology Division of APA, and president the Academy of Behavioral Medicine Research. He is active in graduate education, and has supervised >24 doctoral dissertations in Medical and Clinical Psychology, trained 11 post-doctoral fellows, and currently has 2 Ph.D. students in his lab.

Dr. Krantz is not accepting new students into his lab during the academic year 2021-2022.

Representative publications, projects, and/or deployments

The BETRHEART STUDY (Behavioral Triggers of Heart Failure), examines psychological and biological antedents of hospitalizations, mortality, and worsened functional status in heart failure patients. Reprints of articles from the BETRHEART study are posted on ResearchGate here: https://www.researchgate.net/project/BETRHEART

The KRANTZ HEALTH OPINION SURVEY (KHOS) SCALE for measuring healthcare treatment preferences: Those wanting to use the KHOS can download it as well as the original scale development/validation article by Krantz et al. (1980) from ResearchGate at: https://www.researchgate.net/publication/318661272_Copy_of_Krantz_Health_Opinion_Survey_KHOS_Scale_DOI_1013140RG221274670. This scale is freely available for research; prior permission from the author is not needed as long as the validation article is cited.

To read about the SYSTEMIC DISORDER MODEL OF PTSD, see an advance preprint of the article (in press, Health Psychology) by Krantz DS, Shank LM, Goodie JL. Post-Traumatic Stress Disorder (PTSD) as a Systemic Disorder: Pathways to Cardiovascular Disease, posted here: https://psyarxiv.com/cq9um/


Krantz DS. Shank LM, Goodie JL. PTSD as a Systemic Disorder: Pathways to Cardiovascular Disease. Health Psychology, in press. Preprint DOI: 10.31234/osf.io/cq9um

Krantz DS, Harris KM, Rogers HL, Whittaker KS, Haigney MCP, Kop WJ. Psychological factors and cardiac repolarization instability during anger in implantable cardioverter defibrillator patients. Ann Noninvasive Electrocardiol. 2021 Apr 3:e12848. doi: 10.1111/anec.12848. Online ahead of print. PMID: 33813750

Harris KM, Gottdiener JS, Gottlieb SS, Burg MM, Li S, Krantz DS. Impact of Mental Stress and Anger on Indices of Diastolic Function in Patients With Heart Failure. J Card Fail. 2020 Aug 1;. doi: 10.1016/j.cardfail.2020.07.008. [Epub ahead of print] PubMed PMID: 32750485.

Endrighi R, Dimond AJ, Waters AJ, Dimond CC, Harris KM, Gottlieb SS, Krantz DS. Associations of perceived stress and state anger with symptom burden and functional status in patients with heart failure. Psychology and Health. 2019 Oct;34(10):1250-1266. doi:10.1080/08870446.2019.1609676.

Biggs QM, Ursano RJ, Wang J, Krantz DS, Carr RB, Wynn GH, Adams DP, Dacuyan NM, Fullerton CS. Daily variation in post traumatic stress symptoms in individuals with and without probable post traumatic stress disorder. BMC Psychiatry. 2019 Feb 4;19(1):56. doi: 10.1186/s12888-019-2041-7.

Harris KM, Krantz DS, Kop WJ, Marshall J, Robinson SW, Marshall JM, Gottlieb SS. A New Clinically Applicable Measure of Functional Status in Patients With Heart Failure: The 60-Foot Walk Test. JACC Heart Fail. 2017 Jun;5(6):411-420. doi: 10.1016/j.jchf.2017.02.005. Epub 2017 May 10. PMID: 28501523

Endrighi R, Waters AJ, Gottlieb SS, Harris KM, Wawrzyniak AJ, Bekkouche NS, Li Y, Kop WJ, Krantz DS. Psychological stress and short-term hospitalisations or death in patients with heart failure. Heart. 2016 Jun 29. pii: heartjnl-2015-309154. doi: 10.1136/heartjnl-2015-309154. [Epub ahead of print] PMID: 27357124

Wawrzyniak AJ, Dilsizian V, Krantz DS, Harris KM, Smith MF, Shankovich A, Whittaker KS, Rodriguez GA, Gottdiener J, Li S, Kop W, Gottlieb SS. High Concordance Between Mental Stress-Induced and Adenosine-Induced Myocardial Ischemia Assessed Using SPECT in Heart Failure Patients: Hemodynamic and Biomarker Correlates. J Nucl Med. 2015 Oct;56(10):1527-33. doi: 10.2967/jnumed.115.157990. Epub 2015 Jul 23. PMID: 26205303

Gottlieb SS, Harris K, Todd J, Estis J, Christenson RH, Torres V, Whittaker K, Rebuck H, Wawrzyniak A, Krantz DS. Prognostic significance of active and modified forms of endothelin 1 in patients with heart failure with reduced ejection fraction. Clin Biochem. 2015 Mar;48(4-5):292-6. doi: 10.1016/j.clinbiochem.2014.12.012. Epub 2014 Dec 23. PubMed PMID: 25541019; PubMed Central PMCID: PMC4363211.

Krantz DS, Burg MM. Current perspective on mental stress-induced myocardial ischemia. Psychosom Med. 2014 Apr;76(3):168-70. doi: 10.1097/PSY.0000000000000054. PMID: 24677165