David S. Krantz


Department of Primary Appointment:
School of Medicine
Medical and Clinical Psychology
Emeritus Professor of Medical and Clinical Psychology; Emeritus Professor of Psychiatry (secondary)
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Behavioral medicine and cardiovascular disease
Psychosocial stress and human health


Education: B.S. (1971) in Psychology, City College of New York.
Ph.D. (1975) in Psychology, University of Texas at Austin.


Dr. Krantz is Emeritus Professor in the Department of Medical and Clinical Psychology and Emeritus Professor of Psychiatry at USUHS. Since beginning his career as a health psychologist, he has conducted interdisciplinary research on the role of psychological factors in cardiovascular disease, and the effects of psychosocial stress on health. The focus of this research has been on the effects of acute and chronic stress as trigger of coronary heart disease events, and he has published nearly 200 scientific and professional papers in these areas. He is Principal Investigator of the BETRHEART Study, which investigates stress and psychosocial factors in the progression of heart failure. He also collaborates with investigators in the USUHS Center for the Study of Traumatic Stress on studies of the relationship of post-traumatic stress disorder (PTSD) to incidence of cardiovascular disease, and on moderators of this relationship (e.g., co-occurring conditions such as metabolic risk factors, depression, and sleep) among active-duty service members. He particularly interested in understanding relationships of PTSD to cardiovascular disease and other physical health problems, with an emphasis on PTSD as a "whole body" systemic disorder, rather than as a purely mental health problem.

Dr. Krantz was formerly Chair of the Department of Medical and Clinical Psychology at USUHS between 1999-2014, and was one of a group of founders of the USU Center for Deployment Psychology (CDP), and CDP Principal Investigator between 2006-2015. In the past, he has served as Editor-in-Chief of the APA journal Health Psychology, president of the Health Psychology Division of APA, and president the Academy of Behavioral Medicine Research. He has been active in graduate education, and has supervised 25 doctoral dissertations in Medical and Clinical Psychology, and trained 11 post-doctoral fellows.

Please note: Dr. Krantz is no longer accepting new students into his lab.

Representative publications, projects, and/or deployments

The KRANTZ HEALTH OPINION SURVEY (KHOS) SCALE for measuring healthcare treatment preferences is freely available for research; prior permission from the author is NOT needed as long as the validation article by Krantz et al. (1980) is cited. Those wanting to use the KHOS can download it, together with the original scale development/validation article, from ResearchGate at: https://www.researchgate.net/publication/318661272_Copy_of_Krantz_Health_Opinion_Survey_KHOS_Scale_DOI_1013140RG221274670.

The BETRHEART STUDY (Behavioral Triggers of Heart Failure), examines psychological and biological antedents of hospitalizations, mortality, and worsened functional status in heart failure patients. Reprints of articles from the BETRHEART study are posted on ResearchGate here: https://www.researchgate.net/project/BETRHEART

Current research on PTSD as a "systemic disorder", and how this helps understand the relationship of PTSD to cardiovascular disease and other health problems. To read about this model, see Krantz DS, Shank LM, Goodie JL. Post-Traumatic Stress Disorder (PTSD) as a Systemic Disorder: Pathways to Cardiovascular Disease. Full text here: https://www.researchgate.net/publication/353935019 or PMC full text: https://pubmed.ncbi.nlm.nih.gov/34807673


Moorehead NR, Goodie JL, Krantz DS. Prospective Bidirectional Relations Between Depressive Symptoms and Metabolic Health: 30 Year Follow-up from the NHLBI CARDIA Study. Health Psychology, in press. Preprint in: medRxiv. 2023. Mar 10. doi:10.1101/2023.03.08.23286983

Harris KM, Gaffey AE, Schwartz JE, Krantz DS, Burg MM. The Perceived Stress Scale as a Measure of Stress: Decomposing Score Variance in Longitudinal Behavioral Medicine Studies [published online ahead of print, 2023 Apr 21]. Ann Behav Med. 2023;kaad015. doi:10.1093/abm/kaad015

Krantz DS, Shank LM, Goodie JL. Post-traumatic stress disorder (PTSD) as a systemic disorder: Pathways to cardiovascular disease. Health Psychol. 2022 Oct; 41(10): 651-662. Epub 2021 Nov 22. doi:10.1037/hea0001127. Full text at: www.ncbi.nlm.nih.gov/pmc/articles/PMC9124241/ or www.researchgate.net/publication/353935019

Virzi NE, Krantz DS, Bittner VA, et al. Depression Symptom Patterns as Predictors of Metabolic Syndrome and Cardiac Events in Symptomatic Women with Suspected Myocardial Ischemia: The Women's Ischemia Syndrome Evaluation (WISE and WISE-CVD) Projects. Heart Mind (Mumbai). 2022;6(4):254-261.

Soufer R, Krantz DS. The interaction of biology and emotion: Uncovering a new phenotype of non-obstructive coronary artery disease. Biological Psychiatry, 2022 Vol. 91 (7) 606-608. DOI: 10.1016/j.biopsych.2022.01.005 . Full text at: https://www.researchgate.net/publication/359064673

Fisher JE, Krantz DS, Ogle CM, Zhou J, Zuleta RF, Strickman AK, Fullerton CS, Ursano RJ. Ogle CM, Zhou J, Srickman AM, Fullerton CS, Ursano RJ, Cozza SJ. Mental Health, Ill-Defined Conditions, and Healthcare Utilization Following Bereavement: A Prospective Case-Control Study. Academy of Consultation-Liaison Psychiatry, 2022. DOI: 10.4103/hm.hm_34_21

Krantz DS, Harris KM, Rogers HL, Whittaker KS, Haigney MCP, Kop WJ. Psychological factors and cardiac repolarization instability during anger in implantable cardioverter defibrillator patients. Ann Noninvasive Electrocardiol. 2021 Jul;26(4):e12848. doi: 10.1111/anec.12848. Epub 2021 Apr 3. PMID: 33813750

Harris KM, Gottdiener JS, Gottlieb SS, Burg MM, Li S, Krantz DS. Impact of Mental Stress and Anger on Indices of Diastolic Function in Patients With Heart Failure. J Card Fail. 2020 Aug 1;. doi: 10.1016/j.cardfail.2020.07.008. [Epub ahead of print] PubMed PMID: 32750485.

Biggs QM, Ursano RJ, Wang J, Krantz DS, Carr RB, Wynn GH, Adams DP, Dacuyan NM, Fullerton CS. Daily variation in post traumatic stress symptoms in individuals with and without probable post traumatic stress disorder. BMC Psychiatry. 2019 Feb 4;19(1):56. doi: 10.1186/s12888-019-2041-7.

Endrighi R, Waters AJ, Gottlieb SS, Harris KM, Wawrzyniak AJ, Bekkouche NS, Li Y, Kop WJ, Krantz DS. Psychological stress and short-term hospitalisations or death in patients with heart failure. Heart. 2016 Jun 29. pii: heartjnl-2015-309154. doi: 10.1136/heartjnl-2015-309154. [Epub ahead of print] PMID: 27357124