David Mears


Department of Primary Appointment:
School of Medicine
Anatomy, Physiology and Genetics
Basic Science Co-Director, Neuroscience Module and Interim Chair
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Medical Education
Office Phone


Ph.D., Biomedical Engineering, Johns Hopkins University, 1996
B.S., Biomedical Engineering, Boston University, 1989

Career Highlights: Positions, Projects, Deployements, Awards and Additional Publications

Chair, Council of Module Directors, USU School of Medicine, 2017-

Dean's Faculty Teaching Award, USU School of Medicine, 2016

Outstanding Civilian Educator Award, USU School of Medicine, 2013

Representative Bibliography

Mears D, Pollard HB. Network science and the human brain: using graph theory to understand the brain and one of its hubs, the amygdala, in health and disease. J. Neurosci. Res. 94(6):590-605, 2016

Llanos P, Valencia M, Barrientos G, Hidalgo C, Mears D. Glucose-dependent insulin secretion in pancreatic β-cells requires Ca2+ signals generated by redox stimulation of ryanodine receptors. PLOS 1 10(6): e0129238. doi:10.1371/journal.pone.0129238, 2015

Mears D, Zimliki CL, Atwater I, RojasE, Glassman M, Leighton X, Pollard HB, Srivastava M. The Anx7(+/-) knockout mutation alters electrical and secretory responses to Ca2+-mobilizing agents in pancreatic β-cells. Cell Physiol. Biochem 29:697-704, 2012.

Verma R, Xu X, Jaiswal MK, Olsen C, Mears D, Caretti G, Galdzicki Z. In vitro profiling of epigenetic modifications underlying heavy metal toxicity of tungsten-alloy and its components. Toxicol. Appl. Pharmacol. 253:178-87, 2011.

Contreras-Ferrat AE, Toro B, Bravo R, Parra V, Vásquez C, Ibarra C, Mears D, Chiong M, Jaimovich E, Klip A, Lavandero S. An inositol 1,4,5-triphosphate (IP3) receptor pathway is required for insulin-stimulated glucose transporter 4 translocation and glucose uptake in cardiomyocytes. Endocrinology 151:4665-77, 2010.

Atwater I, Guajardo M, Caviedes P, Jeffs S, Parrau D, Valencia M, Romero C, Arriagada C, Caamaño E, Salas A, Olguin F, Atlagich M, Maas R, Mears D, Rojas E. Isolation of viable porcine islets by selective osmotic shock without enzymatic digestion. Transplant Proc. 42:381-6, 2010.