David Regis


Captain, Navy

Department of Primary Appointment:
School of Medicine
Program Manager - Deep Submergence Biomedical Development
Location: Other Location
Research Interests:
Undersea Medicine - Decompression Illness
Pediatric Infectious Diseases
Office Phone


- Uniformed Services University of the Health Sciences, F. Edward Hébert School of Medicine, Bethesda, MD - Doctor of Medicine
- College of the Holy Cross, Worcester, MA - Bachelor of Arts, Major: Chemistry


CAPT Regis received his commission as Ensign in the U.S. Navy upon matriculation to the Uniformed Services University of the Health Sciences (USU) F. Edward Hébert School of Medicine. He completed his residency in Pediatrics in 1998 as part of the first Joint Class of the National Capital Consortium (NCC) and served his utilization tour at the USNH Guam as a Staff Pediatrician and Head of Pediatrics before returning to NCC to complete a Fellowship in Pediatric Infectious Disease. CAPT Regis completed one year as Chief of Pediatric Infectious Diseases at then National Naval Medical Center Bethesda in 2004 before taking over as Director of Clinical Trials for the Navy’s Malaria Vaccine Program at the Naval Medical Research Center (NMRC) in Silver Spring, MD where he was responsible for testing one of the first adenovirus vectored malaria vaccines in humans. He then went on to complete Undersea Medical Officer training and was assigned to various Undersea Medicine research positions including Head of Biomedical Research at the Navy Experimental Diving Unit, Panama City, FL and Head of Undersea Medicine at NMRC where under his leadership the program expanded its research portfolio to include a new alternobaric research suite. He was then selected for a two year tour as an Undersea Medicine Exchange Officer to the Royal Navy at the Institute of Naval Medicine in Alverstoke, UK after which he successfully screened and was assigned as the Executive Officer to the Naval Submarine Medical Research Laboratory, Groton, CT. He currently serves at the Naval Sea Systems Command as the UMO for the Navy Supervisor of Diving & Salvage (SUPSALV) as well as the Program Manager for the Deep Submergence Biomedical Development Program. He is also a voting member of the Navy Bureau of Medicine Undersea Medicine Working Group. He has taught various lectures at USU in infectious diseases and diving medicine and has served as a member of the NASA Human Research Program Human Health Countermeasures Decompression Sickness Risk Standing Review Panel among other committees.

Career Highlights: Positions, Projects, Deployements, Awards and Additional Publications

Prior USN Diving Medical Exchange Officer with the British Royal Navy, Portsmouth, UK

Member of NASA Human Research Program Human Health Countermeasures Decompression Sickness Risk Standing Review Panel

Qualified as Submarine, Diving and Saturation Diving Medical Officer

Certified in Tropical & Travel Medicine – American Society of Tropical Medicine & Hygiene

Tested the first Adenovirus-5-vectored malaria vaccine for the Navy

Representative Bibliography

Forbes AS, Regis DP, Hall AA, Mahon RT, Cronin WA Propranolol Effects on Decompression Sickness in a Simulated DISSUB Rescue in Swine Aerosp Med Hum Perform. 2017; 88(4):385–391

Petersen K, Regis DP Safety of Antimalarial Medications for Use while Scuba Diving in Malaria Endemic Regions. Tropical Diseases, Travel Medicine and Vaccines 2016; 2:23

Cronin WA, Senese AL, Arnaud FG, Regis DP, Auker CR, Mahon RT The effect of the perfluorocarbon emulsion Oxycyte on platelet count and function in the treatment of decompression sickness in a swine model. Blood Coagul Fibrinolysis 2016; 27(6):702-710

Sheppard RL, Regis DP, Mahon RT Dodecafluoropentane (DDFPe) and Decompression Sickness-Related Mortality in Rats Aerosp Med Hum Perform. 2015; 86(1):21-26.

Richard T. Mahon and David P. Regis Decompression and Decompression Sickness Compr Physiol 4:1157-1175, 2014

Seth Y. Flagg, David P. Regis, Kyle Petersen, Richard T. Mahon Interrupted oxygen pre-breathing and decompression outcomes in swine. Aviat Space Environ Med 84 (1), January 2013 , 12-16(5)

Tamminga C, Sedegah M, Regis D, Chuang I, Epstein JE, Spring M, Mendoza-Silveiras J, McGrath S, Maiolatesi S, Reyes S, Steinbeiss V, Fedders C, Smith K, House B, Ganeshan H, Lejano J, Abot E, Banania GJ, Sayo R, Farooq F, Belmonte M, Murphy J, Komisar J, Williams J, Shi M, Brambilla D, Manohar N, Richie NO, Wood C, Limbach K, Patterson NB, Bruder JT, Doolan DL, King CR, Diggs C, Soisson L, Carucci D, Levine G, Dutta S, Hollingdale MR, Ockenhouse CF, Richie TL. Adenovirus-5-vectored P. falciparum vaccine e

Sedegah M, Tamminga C, McGrath S, House B, Ganeshan H, Lejano J, Abot E, Banania GJ, Sayo R, Farooq F, Belmonte M, Manohar N, Richie NO, Wood C, Long CA, Regis D, Williams FT, Shi M, Chuang I, Spring M, Epstein JE, Mendoza-Silveiras J, Limbach K, Patterson NB, Bruder JT, Doolan DL, King CR, Soisson L, Diggs C, Carucci D, Dutta S, Hollingdale MR, Ockenhouse CF, Richie TL. PLoS One. 2011;6(10):e24586

Regis, DP Manned Testing of the “Standard Configuration” Divex Shadow Excursion UBA for the USMC, NEDU Technical Report 10-05, May 2010

Regis, DP, Dobaño, C, Quiñones-Olson, P, Liang, X, Graber, NL, Stefaniak, ME, Campo, JJ, Carucci, DJ, Roth, DA, He, H, Felgner, PL, Doolan, DL Transcriptionally Active Pcr For Antigen Identification And Vaccine Development: In Vitro Genome-Wide Screening And In Vivo Immunogenicity. Molecular and Biochemical Parasitology 158(1):32-45 (2008).