Kathleen B Madden

PhD

Department of Primary Appointment:
School of Medicine
Pediatrics
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Mucosal Immunology
Immunoparasitology
Email
kathleen.madden@usuhs.edu
Office Phone
(301) 295-3414
Department Website
Department of Pediatrics

Education

1979 B.A., Biology, New York University, New York, NY
1987 Ph.D., Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA

Biography

Dr. Madden received her B.A. in Biology from New York University in 1979, and her Ph.D. in Veterinary and Animal Sciences from the University of Massachusetts in 1987. After completing an initial postdoctoral fellowship at the Animal Parasitology Institute at the USDA in Beltsville, MD, she accepted a second postdoctoral position in the laboratory of Dr. Ildy Katona in the Department of Pediatrics, USUHS, in 1989, and became a member of the pediatric faculty in 1992. Dr. Madden's research interests are primarily in the area immunology, with special emphasis on host-parasite interactions at mucosal surfaces.

Representative Bibliography

Sun, R., J.F. Urban, Jr., L. Notari, T. Vanuytsel, K.B. Madden, J.A. Bohl, T.R. Ramalingam, T.A. Wynn, A. Zhao, and T. Shea-Donohue. 2016. IL-13Ra1-dependent responses in the intestine are critical to parasite clearance. Infect. Immun. 84:1032-1044.

Zhao, A., J.F. Urban, Jr., R. Sun, J. Stiltz, M. Morimoto, L. Notari, K.B. Madden, Z. Yang, V. Grinchuk, T.R. Ramalingam, T.A. Wynn, and T. Shea-Donohue. 2010. Critical role of IL-25 in nematode infection-induced alterations in intestinal function. J. Immunol. 185:6921-6929.

Madden, K.B., K. Au Yeung, A. Zhao, W.C. Gause. F.D. Finkelman, I.M. Katona, J.F. Urban, Jr., and T. Shea-Donohue. 2004. Enteric nematodes induce stereotypic alterations in intestinal epithelial cell function. J. Immunol. 172:5616-5621.

Madden, K.B., L. Whitman, C. Sullivan, W.C. Gause, D.D. Donaldson, J.F. Urban, Jr., I.M. Katona, F.D. Finkelman, and T. Shea-Donohue. 2002. Role of Stat6 and mast cells in IL-4- and IL-13-induced alterations in epithelial cell function. J. Immunol. 169:4417-4422.

Madden, K.B., J.F. Urban, Jr., H.J. Ziltner, J.W. Schrader, F.D. Finkelman, and I.M. Katona. 1991. Antibodies to IL-3 and Il-4 suppress helminth-induced intestinal mastocytosis. J. Immunol. 147:1387-1391.