Kryslaine Lopes Radomski

Ph.D.

Department of Primary Appointment:
School of Medicine
Anatomy, Physiology and Genetics
Title
Research Assistant Professor
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Traumatic brain injury, white matter pathology
Glial cell biology
Office Phone

Education

Post-doctoral Training, Center for Neuroscience and Regenerative Medicine
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD

Post-doctoral Training, Department of Neurosciences
University of California - San Diego, La Jolla, CA

Ph.D., Interdisciplinary Program in Biomedical Sciences, Neuroscience Concentration
College of Medicine, University of Florida, Gainesville, FL

B.S., with honors, Biological Sciences; Minor in Chemistry
College of Liberal Arts and Sciences, Illinois State University, Normal, IL

Representative Bibliography

Persistent hypersomnia following repetitive mild experimental traumatic brain injury: Roles of chronic stress and sex differences. Portillo E, Zi X, Kim Y, Tucker LB, Fu A, Miller LA, Valenzuela KS, Sullivan GM, Gauff AK, Yu F, RADOMSKI KL, McCabe JT, Armstrong RC. J Neurosci Res. 2023 Jan 9. doi: 10.1002/jnr.25165. PMID: 36624699

Acute axon damage and demyelination are mitigated by 4-aminopyridine (4-AP) therapy after experimental traumatic brain injury. RADOMSKI KL, Zi X, Lischka FW, Noble MD, Galdzicki Z, Armstrong RC. Acta Neuropathol Commun. 2022 May 2;10(1):67. doi: 10.1186/s40478-022-01366-z. PMID: 35501931

Repetitive Blast Exposure Produces White Matter Axon Damage without Subsequent Myelin Remodeling: In Vivo Analysis of Brain Injury Using Fluorescent Reporter Mice. Bradshaw DV Jr, Kim Y, Fu A, Marion CM, RADOMSKI KL, McCabe JT, Armstrong RC. Neurotrauma Rep. 2021 Mar 31;2(1):180-192. doi: 10.1089/neur.2020.0058. eCollection 2021. PMID: 34013219

Genetic inactivation of SARM1 axon degeneration pathway improves outcome trajectory after experimental traumatic brain injury based on pathological, radiological, and functional measures. Bradshaw DV Jr, Knutsen AK, Korotcov A, Sullivan GM, RADOMSKI KL, Dardzinski BJ, Zi X, McDaniel DP, Armstrong RC. Acta Neuropathol Commun. 2021 May 17;9(1):89. doi: 10.1186/s40478-021-01193-8. PMID: 34001261

Detection and Distinction of Mild Brain Injury Effects in a Ferret Model Using Diffusion Tensor MRI (DTI) and DTI-Driven Tensor-Based Morphometry (D-TBM). Hutchinson EB, Schwerin SC, RADOMSKI KL, Sadeghi N, Komlosh ME, Irfanoglu MO, Juliano SL, Pierpaoli C. Front Neurosci. 2018 Aug 17;12:573. doi: 10.3389/fnins.2018.00573. eCollection 2018. PMID: 30174584

Experimental Traumatic Brain Injury Identifies Distinct Early and Late Phase Axonal Conduction Deficits of White Matter Pathophysiology, and Reveals Intervening Recovery. Marion CM, RADOMSKI KL, Cramer NP, Galdzicki Z, Armstrong RC. J Neurosci. 2018 Oct 10;38(41):8723-8736. doi: 10.1523/JNEUROSCI.0819-18.2018. Epub 2018 Aug 24. PMID: 30143572

Progression of histopathological and behavioral abnormalities following mild traumatic brain injury in the male ferret. Schwerin SC, Chatterjee M, Imam-Fulani AO, RADOMSKI KL, Hutchinson EB, Pierpaoli CM, Juliano SL. J Neurosci Res. 2018 Apr;96(4):556-572. doi: 10.1002/jnr.24218. Epub 2018 Jan 23. PMID: 29360208

Leukemia/lymphoma-related factor (LRF) exhibits stage- and context-dependent transcriptional controls in the oligodendrocyte lineage and modulates remyelination. Davidson NL, Yu F, Kijpaisalratana N, Le TQ, Beer LA, RADOMSKI KL, Armstrong RC. J Neurosci Res. 2017 Dec;95(12):2391-2408. doi: 10.1002/jnr.24083. Epub 2017 May 30. PMID: 28556945

Establishing the ferret as a gyrencephalic animal model of traumatic brain injury: Optimization of controlled cortical impact procedures. Schwerin SC, Hutchinson EB, RADOMSKI KL, Ngalula KP, Pierpaoli CM, Juliano SL. J Neurosci Methods. 2017 Jun 15;285:82-96. doi: 10.1016/j.jneumeth.2017.05.010. Epub 2017 May 10. PMID: 28499842

Repetitive Model of Mild Traumatic Brain Injury Produces Cortical Abnormalities Detectable by Magnetic Resonance Diffusion Imaging, Histopathology, and Behavior. Yu F, Shukla DK, Armstrong RC, Marion CM, RADOMSKI KL, Selwyn RG, Dardzinski BJ. J Neurotrauma. 2017 Apr 1;34(7):1364-1381. doi: 10.1089/neu.2016.4569. Epub 2016 Dec 20. PMID: 27784203