Robert E Goldstein


Department of Primary Appointment:
School of Medicine
Professor of Medicine and Physiology
Location: Uniformed Services University of the Health Sciences, Bethesda, MD
Research Interests:
Clinical Cardiology
Cardiovascular Physiology and Pharmacology
Office Phone


Harvard College A.B. summa cum laude 1961
Harvard Medical School M.D. magna cum laude 1965
Internal Medicine Residency at Bronx Municipal Hospital Center, Bronx NY 1965-1967


Dr. Goldstein has engaged in cardiovascular medicine and cardiovascular research since he was a medical student. He continues a long career of patient care and teaching at Walter Reed National Military Medical Center. His ongoing focus as a teacher has been enhanced physician performance during bedside or clinic patient evaluation, particularly the physical examination. His research interests have included the pathophysiology and management of coronary artery disease and, more recently, congestive heart failure and arrhythmias. Actively maintaining a long-standing collaboration with the Heart Research Follow-up Program at the University of Rochester, he now serves as Chair of Data and Safety Monitoring Boards for 3 current studies of management for cardiac patients. He also performs collaborative research utilizing extensive databases at the University of Rochester. Since he stepped down as Chair of the USU Department of Medicine, he has collaborated with members of the Cardiology Division to investigate how drugs and clinical conditions influence the electrical activity of cardiac myocytes to sustain stable cardiac rhythm. Dr. Goldstein has exercised leadership roles in the community--President of the Maryland Affiliate of the American Heart Association, Governor (USPHS) for the American College of Cardiology, and currently member of a VA Study Section. At USU, he has been faculty leader of the Alpha Omega Alpha Chapter and member of the Faculty Senate. He has received many distinctive awards in cardiology and medicine, including national recognition as a Guggenheim Fellow and as a Master of the American College of Physicians.

Career Highlights: Positions, Projects, Deployements, Awards and Additional Publications

Westinghouse Science Talent Search Finalist 1957

Alpha Omega Alpha Honor Medical Society, elected 1964; Faculty Councilor for USU Chapter 2000-2013

Cardiology Branch, National Heart, Lung, and Blood Institute, Clinical Associate 1967-1970, Senior Investigator 1971-1980

John Simon Guggenheim Fellow, St. George's Hospital, London 1974-1975

Commissioned Corps, US Public Health Service, 1967-1998; CAPT and Senior PHS Officer at USU 1980-1998

FDA Cardiorenal Advisory Committee, 1982-1985

Fellow, American College of Physicians 1972-, Master, American College of Physicians, 2002-

Fellow, American College of Cardiology 1976-, Governor for the US Public Health Service 1981-1984

Director for Cardiology, Department of Medicine, USU 1984-1996

Chair, Department of Medicine, USU 1996-2006

Representative Bibliography

Goldstein, R.E., and Epstein, S.E.: The mechanism of elevated innominate artery pressures in supravalvular aortic stenosis. Circulation 42:23-29, 1970.

Goldstein, R.E., Redwood, D.R., Rosing, D.R., Beiser, G.D., and Epstein, S.E.: Alterations in the circulatory response to exercise following a meal and their relationship to postprandial angina pectoris. Circulation 44:90-100, 1971.

Goldstein, R.E., Stinson, E.B., Grehl, T.M., Scherer, J.L., Seningen, R.P., and Epstein, S.E.: Intraoperative coronary collateral function in patients with coronary occlusive disease. Nitroglycerin responsiveness and angiographic correlations. Circulation 49:298-308, 1974.

Goldstein, R.E.: Coronary vascular responses to vasodilator drugs. Progress in Cardiovasc. Dis. 24:419-436, 1982.

Goldstein, R.E., Oetgen, W.J., and Tibbits, P.A.: Proarrhythmic effects of antiarrhythmic drugs. Ann. N.Y. Acad. Sci. 427:94-100, 1984.

Goldstein, R. E., Boccuzzi, S.J., Cruess, D., Nattel, S., the Adverse Experience Committee, and the Multicenter Diltiazem Postinfarction Research Group: Diltiazem increases late-onset congestive heart failure in postinfarction patients with early reduction in ejection fraction. Circulation 83:52-60, 1991.

Goldstein, R.E., Boccuzzi, S.J., Cruess, D., and the Multicenter Diltiazem Postinfarction Trial Research Group: Prognosis after hospitalization for acute myocardial infarction not accompanied by typical ischemic chest pain. Am. J. Med. 99:123-131, 1995.

Goldstein R.E., Haigney M.C., Krone R.J., McNitt S., Zareba W, and Moss A.J. Differing effects of cardiac resynchronization therapy on long-term mortality in patient subgroups of MADIT-CRT defined by baseline conduction and one-year post-treatment left ventricular remodeling. Heart Rhythm 2013;10:366-373.

Klein M.G., Shou M., Stohlman J., Haigney M., Tidwell R.R., Goldstein R.E., Flagg, T.P., and Haigney, M.C. Role of Suppression of the Inward Rectifier Current (IK1) on Terminal Action Potential Repolarization in the Failing Heart. Heart Rhythm 2017;14: 1217-1223.