William Theodore MD

Education

BA. Harvard College 1969
MD Columbia University College of Physicians and Surgeons 1974
Internal Medicine Residency Roosevelt Hospital NYC 1974-6
Neurology Residency Mt Sinai Hospital NYC 1976-9
Clinical Neurophysiology and Epilepsy Fellowship NIH 1979-1981

Biography

I served until 2021 as Chief of the Clinical Epilepsy Section NINDS and Professor of Neurology at the Uniformed Services University of the Health Sciences. I continue to perform research as an intramural Senior Investigator. As Section Chief, I received continuous funding from the NINDS Division of Intramural research since 1988. In addition to performing clinical and translational research, I have provided care to patients with epilepsy, at the NIH Clinical Center, National Naval Medical Center, and Walter Reade Army Medical Center, and performed clinical research in epilepsy since 1979. I have extensive experience in clinical and translational research in patients with drug-resistant epilepsy, including a series of experimental drug trials, fMRI for language and memory mapping, and neurotransmitter receptor imaging. More recently I have worked on PET imaging of inflammation, and viral etiologies of epilepsy. I am Board-Certified in Internal Medicine, Neurology, Clinical Neurophysiology and Epilepsy. I have trained more than 50 fellows, many of whom have pursued careers as clinical and translational epilepsy investigators. I have been very active in national and international organizations, including the American Epilepsy Society, International League Against Epilepsy, and American Academy of Neurology. I have served as a consultant for the Pan American Health Organization, and the World Health Organization in South East Asia, and as a collaborator on cysticercosis research in Peru. Supported by the World Federation of Neurology and the International League Against Epilepsy I have made four trips to serve as Visiting Professor at the University of Zambia in Lusaka where I performed direct patient care as well as teaching and research. My full bibliography can be found at http://www.ncbi.nlm.nih.gov/myncbi/collections/bibliography/49336698/

Career Highlights: Positions, Projects, Deployements, Awards and Additional Publications

1988—2021: Chief, Clinical Epilepsy Section, MNB, NINDS, DIR, NIH

1991: American Epilepsy Society Clinical Investigator Award

1998-2002: Chairman, International League Against Epilepsy North American Commission

2008—2012: Co-Editor in Chief for Clinical Science, Epilepsy Research

2010--2012: Chair, American Academy of Neurology Epilepsy Section

2011-2014: American Board of Psychiatry and Neurology Epilepsy Examination Development Committee

2016-2019: Treasurer, American Epilepsy Society

2021-2023: Vice-President, American Epilepsy Society

Representative Bibliography

You Z, Zachery AN, Fanto E, Norato G, Germeyan S, Emery EJ, Sepeta LN, Berl MB, Black CL, Wiggs E, Zaghloul K, Inati SK, Gaillard WD, Theodore WH. fMRI Prediction of Naming Change after Adult Temporal Lobe Epilepsy Surgery: Activation Matters. Epilepsia.. 2019;60:527-538. doi: 10.1111/epi.14656.

Rolinski R, Austermuehle A, Wiggs E, Agrawal S, Sepeta L, Gaillard WD, Zaghloul K, Inati SK, Theodore WH. Functional MRI and Direct Cortical Stimulation: Prediction of Postoperative Language Decline. Epilepsia. 2019;60:560-570. doi: 10.1111/epi.14666

Dickstein LP, Liow J-S, Austermuehle A, Zoghbi S, Inati SK, Zaghloul K, Zanotti-Fregonara P, Theodore WH. Neuroinflammation in Neocortical Epilepsy Measured by PET imaging of Translocator Protein. Epilepsia 2019 60(6):1248-1254. PMID: 31144767. DOI: 10.1111/epi.15967

Rolinski R, You X, Gonzalez-Castillo J, Norato G, Reynolds RC, Inati SK, Theodore WH. Language lateralization from task-based and resting state functional MRI in patients with epilepsy. Hum Brain Mapp. 2020 Aug 1;41(11):3133-3146. doi: 10.1002/hbm.25003. Epub 2020 Apr 24.PMID: 32329951

Akinsoji EO, Leibovitch E, Billioux J, Lopes Abath Neto O, Ray-Chaudhury A, Inati SK, Zaghloul K, Heiss J, Jacobson S, Theodore WH. HHV-6 and Hippocampal Volume in Patients with Mesial Temporal Sclerosis. Annals of Clinical and Translational Neurology. 2020 Sep;7(9):1674-1680. doi: 10.1002

Theodore WH. Epilepsy in the Hippocratic Collection: Seizures and Syndromes. Epilepsy and Behavior 2021 Feb;115:107704.doi: 10.1016/j

Austermuehle A, Cocjin J, Reynolds R, Agrawal S, Sepeta L, Gaillard WD, Zaghloul K, Inati S, Theodore WH. Language fMRI and Direct Cortical Stimulation in Epilepsy Preoperative Planning. Annals of Neurology 2017 Feb 21. doi: 10.1002/ana.24899. PMID: 28220524

Siddiqi OK, Elafros MA, Birbeck GL, Sikazwe. I, Kalungwana L, Michael J. Potchen MJ, Bositis CM, Koralnik IJ, Theodore WH. EEG Evaluation of HIV+ Zambian Adults with New-Onset Seizure. Neurology 2015 Mar 31;84(13):1317-22. PMID: 25740861